Correction: The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia
نویسندگان
چکیده
In the "merge" panel of Fig 9, row B, the authors inadvertently inserted the incorrect image. The corrected version of this figure is provided here. Copyright: © 2015 Rangel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia
Hospital-acquired pneumonia is associated with high rates of morbidity and mortality, and dissemination to the bloodstream is a recognized risk factor for particularly poor outcomes. Yet the mechanism by which bacteria in the lungs gain access to the bloodstream remains poorly understood. In this study, we used a mouse model of Pseudomonas aeruginosa pneumonia to examine this mechanism. P. aeru...
متن کاملThe ADP-Ribosyltransferase Domain of the Effector Protein ExoS Inhibits Phagocytosis of Pseudomonas aeruginosa during Pneumonia
UNLABELLED Pseudomonas aeruginosa is a Gram-negative pathogen commonly associated with nosocomial infections such as hospital-acquired pneumonia. It uses a type III secretion system to deliver effector proteins directly into the cytosol of host cells. Type III secretion in P. aeruginosa has been linked to severe disease and worse clinical outcomes in animal and human studies. The majority of P....
متن کاملRelative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung.
Pseudomonas aeruginosa uses a type III secretion system to promote development of severe disease, particularly in patients with impaired immune defenses. While the biochemical and enzymatic functions of ExoU, ExoS, and ExoT, three effector proteins secreted by this system, are well defined, the relative roles of each protein in the pathogenesis of acute infections is not clearly understood. Sin...
متن کاملفراوانی ژن‌های کد کننده سیتوتوکسین‌های exoT، exoY، exoS وexoU سیستم ترشحی تیپ 3 در سودوموناس آئروجینوزا جدا شده از بیماران سوختگی
Background and Objective: Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial burn infections. Disease results from the production of numerous virulence factors, some of which are injected directly into the eukaryotic host cells via the type III secretion system (T3SS).The aim of this study was to determine the prevalence of cytotoxins encoding exoT, exoY, exoS and exoU genes...
متن کاملThe great escape: Pseudomonas breaks out of the lung
The Gram-negative bacterium Pseudomonas aeruginosa is a major cause of hospital-acquired infections and the focus of much attention due to its resistance to many conventional antibiotics. It harbors a wide range of disease-promoting virulence factors, including a type III secretion system. Here we review our recent study of ExoS, one of the effector proteins exported by this type III secretion ...
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عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2015